Cancer and Fertility
2010 OMG! Summit - Oncofertility Panel
How Cancer Can Affect a Man's Fertility
How Cancer Treatment Regimes Can Affect Fertility:
- May cause dose related suppression of spermatogenesis
- Alkylating agents do the most damage
Risk is increased with:
A. Two or more alkylating agents,
B. Higher doses
C. Combination of chemo with radiation
D. High dose cisplatinum/bleomycin
- Examples: Testicular, prostate or bladder cancer surgery
- May cause retrograde ejaculation
How to Preserve Your Fertility Before Treatment:
The most proven and successful method of preserving fertility for male cancer patients. Once the sperm has been frozen and stored in liquid nitrogen, there are no known upper limits on how long it can be preserved. There is a case report of a live birth after 28 years of storage.
How Stored Sperm Can Be Used in the Future:
Fertility Treatment Options with Frozen Sperm:
ICI or IUI:
- This option is for men with semen quality that is closer to normal.
- The best option for men with a limited number of vials or poor quality.
- When there are very few sperm and the quality is low this may be the only option for fertility. One, two or, occasionally, three embryos can be placed into the uterus of the female partner in the hopes that they will implant and start a pregnancy.
Coming soon...information on cancer and female fertility